How the Aminoglutethimide Product Works:
Aminoglutethirnide inhibits the synthesis of adrenal steroids such as glucocorticoids, mineralocorticoids, estrogens and androgens.
Uses of The Aminoglutethimide:
To suppress the adrenal gland functions in selected patients with Cushing syndrome.
Unlabeled Uses: Occasionally doctors may prescribe aminoglutethimide to treat breast cancer in postmenopausal patients or to treat patients with metastatic prostate cancer.
Fell your doctor or pharmacist if you are taking or planning to take any over the-counter or prescription medications or dietary supplements while taking this medicine. Doses of one or both drugs may need to be modified or a different drug may need to be prescribed. The following drugs and drug classes interact with this medicine.
Side Effects of Aminoglutethimide:
Every drug is capable of producing side effects. Most patients experience side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy and individual susceptibility. Possible side effects include:
Digestive Tract: Nausea; appetite loss; vomiting. Nervous System: Drowsiness; headache; dizziness.
Circulatory System: Low blood pressure (occasionally causing dizziness or lightheadedness when rising from sitting or lying); fast heartbeat.
Skin: Rash; itching.
Other: Muscle pain; fever; reduced adrenal function; under active thyroid (eg, weight gain); abnormal blood counts.
Guidelines for Use:
Use exactly as prescribed.
The usual dose is 250 mg four times daily, every 6 hours.
If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose in order to “catch up” (unless advised to do so by your doctor). If more than one dose is missed or it is necessary to establish a new dosage schedule, contact your doctor or pharmacist.
May cause dizziness, lightheartedness or fainting, especially when rising quickly from a sitting or lying. If these symptoms should occur, sit or lie down and contact your doctor. Use caution while driving or performing hazardous tasks requiring alertness, coordination or physical dexterity.
If severe rash, extreme drowsiness, yellowing of skin or eyes, fainting, weakness or headache occur, contact your doctor immediately.
Nausea and loss of appetite may occur during the first 2 weeks of therapy. Contact you doctor if these do not go away.
Contraceptive measures (birth control) are recommended during treatment to avoid birth defects. Contact your doctor if pregnancy is suspected.
Store at room temperature (below 86°F) in a tightly sealed container. Protect from light.